Spatial reconstruction of single-cell gene expression data
نویسندگان
چکیده
منابع مشابه
Spatial reconstruction of single-cell gene expression
Spatial localization is a key determinant of cellular fate and behavior, but spatial RNA assays traditionally rely on staining for a limited number of RNA species. In contrast, single-cell RNAseq allows for deep profiling of cellular gene expression, but established methods separate cells from their native spatial context. Here we present Seurat, a computational strategy to infer cellular local...
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ژورنال
عنوان ژورنال: Nature Biotechnology
سال: 2015
ISSN: 1087-0156,1546-1696
DOI: 10.1038/nbt.3192